Diagnosis of Hip Complaints: Arthritis & Neoplasms Part II | El Paso, TX. Skip to main content

Diagnosis of Hip Complaints: Arthritis & Neoplasms Part II | El Paso, TX.

Ischemic Osteonecrosis

diagnosis hip arthritis and neoplasms el paso, tx.

  • Ischemic Osteonecrosis (More accurate term) aka avascular necrosis AVN: this term describes subarticular (subchondral) bone death
  • Intramedullary bone infarct: depicts osteonecrosis within the medullary cavity of the bone (above x-ray image)
  • Causes: m/c: trauma, systemic corticosteroids, diabetes, vasculitis in SLE. The list is long. Other vital causes: Sickle cell disease, Gaucher disease, alcohol, caisson disease, SCFE, LCP, etc.
  • Pathology: ischemia and bone infarct with resultant devitalized center surrounded by ischemia and edema with normal bone on the outer periphery (MRI double line sign)
  • Sub-articular necrotic bone eventually collapses and fragments leading to progressive bone and cartilage destruction and rapidly progressing DJD
  • Early Dx often missed but crucial to prevent severe DJD

M/C Sites

diagnosis hip arthritis and neoplasms el paso, tx.

  • Hips, shoulders, talus, scaphoid bone. Many peripheral idiopathic AVN sites are known by their eponyms (e.g., Kienbock aka AVN of the lunate bone, Preisier aka scaphoid AVN)
  • Radiography is insensitive to early AVN and may only present as subtle osteopenia
  • Some of the early appreciable rad features are increased patchy bone sclerosis followed by sub-articular bone collapse or "crescent sign" signifying stage-3 on Ficat classification (above)
  • Earliest detection and early intervention can be achieved by MRI (most sensitive modality)
  • If MRI contraindicated or unavailable, 2nd most sensitive modality is radionuclide bone scan (scintigraphy)
  • X-ray and CT scanning are of equal value

Coronal MRI Slice

diagnosis hip arthritis and neoplasms el paso, tx.

  • Fluid sensitive, sensitive coronal MRI slice revealing bill ischemic osteonecrosis of the femoral head
  • MRI findings: l

Tc99-MMDP Radionuclide Bone

diagnosis hip arthritis and neoplasms el paso, tx.

  • Bone scan reveals a central area of photopenia (cold spot) d/t necrotic fragment surrounded by increased osteoblastic activity as increased uptake of Tc-99 MDP in the right hip
  • The patient is a 30-year-old female with breast cancer and chemotherapy treatment who suddenly presented with right hip pain

Radiographic Progression of AVN

diagnosis hip arthritis and neoplasms el paso, tx.

  • Later stages present with articular collapse, subarticular cysts, increased patchy sclerosis and complete flattening of the femoral head with resultant severe DJD. Rx: THA

Management

diagnosis hip arthritis and neoplasms el paso, tx.

  • Early imaging Dx with MRI or bone scintigraphy is essential
  • Referral to the Orthopedic surgeon
  • Core decompression (above) can be used to revascularize the affected bone during earlier stages but produces mixed results
  • Delayed changes of AVN: THA as IN severe DJD cases

B/L THA

diagnosis hip arthritis and neoplasms el paso, tx.

  • B/L THA in the patient with ischemic osteonecrosis of the right and later left hip
  • When B/L hip AVN is present, typically consider systemic causes (corticosteroids, diabetes)

Inflammatory Arthritis Affecting the Hip

diagnosis hip arthritis and neoplasms el paso, tx.

  • Consider common systemic inflammatory condition such as RA and AS/EnA
  • Hip RA may develop in 30% of patients with RA
  • Key features to DDx inflammatory arthritis vs. DJD is symmetrical/uniform aka concentric joint loss often leading to axial migration and Protrusion Acetabule in advanced cases
  • Key element between RA vs. AS: the presence of RA bone erosion w/o productive bone changes or enthesitis in AS d/t inflammatory subperiosteal bone proliferation, whiskering/fluffy periostitis (collar-type enthesitis circumferentially affecting head-neck junction)
  • Dx: Hx, PE, labs: CRP, RH, anti-CCP Ab (RA)
  • CRP, HLA-B27, RF- (AS)

Septic Arthritis

diagnosis hip arthritis and neoplasms el paso, tx.

  • Gonococcal infections, iatrogenic causes, I.V. drug use, and some others
  • Routes: hematogenous, adjacent spread, direct inoculation (e.g., iatrogenic)
  • Clinically: pain and reduced ROM presented as monoarthritis, generalized signs/symptoms. CBC, ESR, CRP changes. ARthrocentesis and culture are crucial
  • M/C pathogen Staph. Aureus & Neisseria Gonorrhea
  • 1st step: radiography, often unrewarding in the early stage. Later (4-10 days) indistinctness of the white cortical line at the femoral articular epiphysis, loss of joint space, effusion as a widening of the medial joint area (Waldenstrom sign)
  • MRI - best at early DX: T1, T2, STIR, T1+C may help with early. Early I.V. antibiotics crucial to prevent rapid joint destruction

Slipped Capital Femoral Epiphysis (SCFE)

diagnosis hip arthritis and neoplasms el paso, tx.

  • Important to diagnose but easily missed potentially leading to Ischemic Osteonecrosis of the femoral head aka AVN
  • Presents typically in overweight children (more often boys), age over 8 years. Greater incidence in African-American boys
  • 1st step: radiography, especially look for a widened physeal growth plate (so-called pre-slip). Later, slip and disturbed Klein's line (above image). MRI - best modality for early Dx and early intervention
  • The frog lateral view often demonstrates the medial slip better than the AP view

Clinically Limping Child or Adolescent

diagnosis hip arthritis and neoplasms el paso, tx.

  • M>F (10-18 years). African-Americans are at greater risk. 20% of cases of SCFE are B/L. Complications: AVN >>DJD
  • Radiography: AP pelvis, spot, and frog leg may reveal slippage as Klein line failed to cross through the lateral aspect of the femoral head
  • Additional features: physis may appear widened
  • MRI w/o gad is required for the earliest Dx and prevention of complications (AVN)

Normal and Abnormal Klein Line

diagnosis hip arthritis and neoplasms el paso, tx.

  • Consistent with SCFE. The physis is also widened. Dx: SCFE
  • Urgent referral to the Pediatric Orthopedic surgeon

Subtle Changes in Left Hip

diagnosis hip arthritis and neoplasms el paso, tx.

  • Note suspected subtle changes in the left hip that may require MR examination to confirm the Dx
  • Delay in care may result in significant complications

Perthes' Disease

diagnosis hip arthritis and neoplasms el paso, tx.

  • aka Legg-Calves-Perthes Disease (LCP)
  • Refers to Osteochondritis of the femoral head with osteonecrosis likely d/t disturbed vascularization of the femoral head
  • Presents typically in children (more often boys) aged under 8 years as atraumatic "limping child." 15% may have B/L Perthe's
  • Imaging steps: 1st step x-radiography, followed by MRI especially in stage 1 (early) w/o x-ray abnormalities
  • Unspecific signs: joint effusion with Waldenstrome sign+ (>2-mm increase in medial joint space compared to the opposite side). Past approach: Fluoroscopic Arthrography (replaced by MRI)
  • Pathologic-Radiologic Correlation: in well-established cases, the femoral head characteristically becomes sclerotic, flattened and fragmented due to avascular necrosis (AVN). Later on, an occasional Coxa Magna changes may develop (>10% femoral head enlargement)
  • Management: symptoms control, bracing. Boys at younger ate show better prognosis d/t more immaturity and better chances of bone/cartilage repair mechanisms. In advanced cases, operative care: osteotomy, hip arthroplasty in adulthood if advanced DJD develops

Common Neoplasms & Other Conditions Affecting Hip/Pelvis

diagnosis hip arthritis and neoplasms el paso, tx.

  • M/C hip & pelvis neoplasms in adults: bone metastasis ( above far left), 2nd m/c Multiple Myeloma (M/C primary bone malignancy in adults). Tips: remember Red Marrow distribution. Less frequent: Chondrosarcoma
  • Paget's disease of bone (above-bottom left image) is m/c detected in the pelvis and Femurs
  • Children and young adults 'limping child' benign neoplasms: Fibrous Dysplasia (above middle image), Solitary Bone Cyst (21%), Osteoid Osteoma, Chondroblastoma. Malignant pediatric neoplasms: m/c Ewing Sarcoma (above middle right and bottom images) vs. Osteosarcoma. >2y.o-consider Neuroblastoma
  • Imaging: 1st step: radiography followed by MRI are most appropriate.
  • If Mets are suspected: Tc99 bone scintigraphy is most sensitive

Multiple Myeloma

diagnosis hip arthritis and neoplasms el paso, tx.

  • Multiple Myeloma in a 75-y.o male (AP pelvis view)
  • Chondrosarcoma in a 60-y.o male (axial and coronal reconstructed CT+C slices in the bone window)

Hip Pelvis Arthritis & Neoplasms

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