Platelet-Rich Plasma, or PRP, is a treatment made from a person's own blood. A provider draws a small blood sample, spins it in a centrifuge, and separates a platelet-rich plasma layer. That concentrated plasma is then injected into an injured area such as a tendon, ligament, muscle, or joint. Platelets are best known for helping blood clot, but they also carry growth factors and signaling proteins that may support tissue repair and healing. As a result, PRP has become a popular non-surgical option in sports medicine and orthopedics. (Johns Hopkins Medicine, n.d.; Yale Medicine, n.d.). What PRP Does Inside the Body The basic idea behind PRP is simple: bring a higher concentration of healing signals to the part of the body that is struggling to recover. After PRP is injected, the platelets release growth factors that may stimulate cell repair, tissue regeneration, collagen production, and a more organized healing response. This is why PRP is often described as a regenerative treatme...
Sciatica is not a diagnosis by itself. It is a symptom pattern that typically involves pain radiating from the lower back to the buttocks, thigh, calf, or foot, often accompanied by numbness, tingling, or weakness. In many cases, the problem begins when a lumbar disc herniation or another spinal structure irritates or compresses a nerve root, especially at L4-L5 or L5-S1. That is why proper care begins with a careful exam, a history of symptoms, and imaging only when it is truly needed or when invasive treatment is being considered. (Zhang et al., 2024; Khorami et al., 2021). What PRP therapy is Platelet-Rich Plasma, or PRP, is made from a sample of the patient's own blood. The blood is spun in a centrifuge to concentrate the platelets. Those platelets carry signaling proteins and growth factors that help regulate healing. Reviews of PRP biology describe effects such as support for cell proliferation, collagen deposition, angiogenesis, tissue remodeling, and inflammatory control. I...